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Productive SV40 Infection of Neurons in Immunosuppressed Rhesus Monkeys

There currently is no animal model of JC virus (JCV)-associated progressive multifocal leukoencephalopathy (PML). Reactivation of simian virus-40 (SV40) in immunosuppressed rhesus monkeys, however, rarely causes a PML-like illness. We sought to isolate a neurotropic clone of SV40 and determine its p...

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Detalhes bibliográficos
Main Authors: Dang, Xin, Wüthrich, Christian, Axthelm, Michael K., Koralnik, Igor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745603/
https://ncbi.nlm.nih.gov/pubmed/18648324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318180f0d5
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