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A speed limit for conformational change of an allosteric membrane protein
Neuromuscular acetylcholine receptors are synaptic ion channels that open and close with rate constants of ≈48,000 s(-1) and ≈1,700 s(-1), respectively (in adult mouse, at 24°C, -100 mV membrane potential). Perturbations of many different sites in the protein can change these rate constants, with th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC544059/ https://ncbi.nlm.nih.gov/pubmed/15618401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406777102 |
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