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Allosteric mechanism in AMPA receptors: A FRET-based investigation of conformational changes
α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the primary mediators of fast excitatory synaptic transmission in the mammalian CNS. Structures of the extracellular ligand-binding domain suggest that the extent of cleft closure in the ligand-binding domain controls the exte...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502482/ https://ncbi.nlm.nih.gov/pubmed/16793923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603225103 |
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