Allosteric mechanism in AMPA receptors: A FRET-based investigation of conformational changes

α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the primary mediators of fast excitatory synaptic transmission in the mammalian CNS. Structures of the extracellular ligand-binding domain suggest that the extent of cleft closure in the ligand-binding domain controls the exte...

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Detaylı Bibliyografya
Asıl Yazarlar: Ramanoudjame, Gomathi, Du, Mei, Mankiewicz, Kimberly A., Jayaraman, Vasanthi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502482/
https://ncbi.nlm.nih.gov/pubmed/16793923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603225103
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