Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial

The RTS,S candidate malaria vaccine can protect against controlled human malaria infection (CHMI), but how protection is achieved remains unclear. Here, we have analyzed longitudinal peripheral blood transcriptome and immunogenicity data from a clinical efficacy trial in which healthy adults receive...

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Bibliographic Details
Published in:Front Immunol
Main Authors: van den Berg, Robert A., Coccia, Margherita, Ballou, W. Ripley, Kester, Kent E., Ockenhouse, Christian F., Vekemans, Johan, Jongert, Erik, Didierlaurent, Arnaud M., van der Most, Robbert G.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440508/
https://ncbi.nlm.nih.gov/pubmed/28588574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00557
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