Predicting RTS,S Vaccine-Mediated Protection from Transcriptomes in a Malaria-Challenge Clinical Trial

The RTS,S candidate malaria vaccine can protect against controlled human malaria infection (CHMI), but how protection is achieved remains unclear. Here, we have analyzed longitudinal peripheral blood transcriptome and immunogenicity data from a clinical efficacy trial in which healthy adults receive...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: van den Berg, Robert A., Coccia, Margherita, Ballou, W. Ripley, Kester, Kent E., Ockenhouse, Christian F., Vekemans, Johan, Jongert, Erik, Didierlaurent, Arnaud M., van der Most, Robbert G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440508/
https://ncbi.nlm.nih.gov/pubmed/28588574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00557
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