A Phase IIa Controlled Human Malaria Infection and Immunogenicity Study of RTS,S/AS01(E) and RTS,S/AS01(B) Delayed Fractional Dose Regimens in Malaria-Naive Adults

BACKGROUND: A previous RTS,S/AS01(B) vaccine challenge trial demonstrated that a 3-dose (0-1-7–month) regimen with a fractional third dose can produce high vaccine efficacy (VE) in adults challenged 3 weeks after vaccination. This study explored the VE of different delayed fractional dose regimens o...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Moon, James E, Ockenhouse, Christian, Regules, Jason A, Vekemans, Johan, Lee, Cynthia, Chuang, Ilin, Traskine, Magali, Jongert, Erik, Ivinson, Karen, Morelle, Danielle, Komisar, Jack L, Lievens, Marc, Sedegah, Martha, Garver, Lindsey S, Sikaffy, April K, Waters, Norman C, Ballou, William Ripley, Ofori-Anyinam, Opokua
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552430/
https://ncbi.nlm.nih.gov/pubmed/32687161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa421
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