A Phase IIa Controlled Human Malaria Infection and Immunogenicity Study of RTS,S/AS01(E) and RTS,S/AS01(B) Delayed Fractional Dose Regimens in Malaria-Naive Adults

BACKGROUND: A previous RTS,S/AS01(B) vaccine challenge trial demonstrated that a 3-dose (0-1-7–month) regimen with a fractional third dose can produce high vaccine efficacy (VE) in adults challenged 3 weeks after vaccination. This study explored the VE of different delayed fractional dose regimens o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Moon, James E, Ockenhouse, Christian, Regules, Jason A, Vekemans, Johan, Lee, Cynthia, Chuang, Ilin, Traskine, Magali, Jongert, Erik, Ivinson, Karen, Morelle, Danielle, Komisar, Jack L, Lievens, Marc, Sedegah, Martha, Garver, Lindsey S, Sikaffy, April K, Waters, Norman C, Ballou, William Ripley, Ofori-Anyinam, Opokua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552430/
https://ncbi.nlm.nih.gov/pubmed/32687161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa421
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