Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

RTS,S is an advanced malaria vaccine candidate and confers significant protection against Plasmodium falciparum infection in humans. Little is known about the molecular mechanisms driving vaccine immunity. Here, we applied a systems biology approach to study immune responses in subjects receiving th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kazmin, Dmitri, Nakaya, Helder I., Lee, Eva K., Johnson, Matthew J., van der Most, Robbert, van den Berg, Robert A., Ballou, W. Ripley, Jongert, Erik, Wille-Reece, Ulrike, Ockenhouse, Christian, Aderem, Alan, Zak, Daniel E., Sadoff, Jerald, Hendriks, Jenny, Wrammert, Jens, Ahmed, Rafi, Pulendran, Bali
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338562/
https://ncbi.nlm.nih.gov/pubmed/28193898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621489114
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