Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

RTS,S is an advanced malaria vaccine candidate and confers significant protection against Plasmodium falciparum infection in humans. Little is known about the molecular mechanisms driving vaccine immunity. Here, we applied a systems biology approach to study immune responses in subjects receiving th...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kazmin, Dmitri, Nakaya, Helder I., Lee, Eva K., Johnson, Matthew J., van der Most, Robbert, van den Berg, Robert A., Ballou, W. Ripley, Jongert, Erik, Wille-Reece, Ulrike, Ockenhouse, Christian, Aderem, Alan, Zak, Daniel E., Sadoff, Jerald, Hendriks, Jenny, Wrammert, Jens, Ahmed, Rafi, Pulendran, Bali
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338562/
https://ncbi.nlm.nih.gov/pubmed/28193898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621489114
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