Systems analysis of protective immune responses to RTS,S malaria vaccination in humans

RTS,S is an advanced malaria vaccine candidate and confers significant protection against Plasmodium falciparum infection in humans. Little is known about the molecular mechanisms driving vaccine immunity. Here, we applied a systems biology approach to study immune responses in subjects receiving th...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kazmin, Dmitri, Nakaya, Helder I., Lee, Eva K., Johnson, Matthew J., van der Most, Robbert, van den Berg, Robert A., Ballou, W. Ripley, Jongert, Erik, Wille-Reece, Ulrike, Ockenhouse, Christian, Aderem, Alan, Zak, Daniel E., Sadoff, Jerald, Hendriks, Jenny, Wrammert, Jens, Ahmed, Rafi, Pulendran, Bali
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338562/
https://ncbi.nlm.nih.gov/pubmed/28193898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621489114
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