Inhibition of Macroautophagy Triggers Apoptosis

Mammalian cells were observed to die under conditions in which nutrients were depleted and, simultaneously, macroautophagy was inhibited either genetically (by a small interfering RNA targeting Atg5, Atg6/Beclin 1-1, Atg10, or Atg12) or pharmacologically (by 3-methyladenine, hydroxychloroquine, bafi...

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Dades bibliogràfiques
Autors principals: Boya, Patricia, González-Polo, Rosa-Ana, Casares, Noelia, Perfettini, Jean-Luc, Dessen, Philippe, Larochette, Nathanael, Métivier, Didier, Meley, Daniel, Souquere, Sylvie, Yoshimori, Tamotsu, Pierron, Gérard, Codogno, Patrice, Kroemer, Guido
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC543994/
https://ncbi.nlm.nih.gov/pubmed/15657430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.3.1025-1040.2005
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