Down-regulation of long non-coding RNA RP11-708H21.4 is associated with poor prognosis for colorectal cancer and promotes tumorigenesis through regulating AKT/mTOR pathway

Long non-coding RNAs (lncRNAs) serve critical roles in cancer development and progression. Herein, through next generation RNA sequencing and experimental validations, we determined the expression status of RP11-708H21.4 in colorectal cancer (CRC) and explored its clinical significance and biologica...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Sun, Longci, Jiang, Chunhui, Xu, Chunjie, Xue, Hanbing, Zhou, Hong, Gu, Lei, Liu, Ye, Xu, Qing
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438619/
https://ncbi.nlm.nih.gov/pubmed/28427191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15846
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