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Thioflavin T fluoresces as excimer in highly concentrated aqueous solutions and as monomer being incorporated in amyloid fibrils

Fluorescence of thioflavin T (ThT) is a proven tool for amyloid fibrils study. The correct model of ThT binding to fibrils is crucial to clarify amyloid fibrils structure and mechanism of their formation. Although there are convincing evidences that ThT has molecular rotor nature, implying it’s bind...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Sulatskaya, Anna I., Lavysh, Andrey V., Maskevich, Alexander A., Kuznetsova, Irina M., Turoverov, Konstantin K.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438369/
https://ncbi.nlm.nih.gov/pubmed/28526838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02237-7
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