Investigation of α-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T

In this work, α-synuclein amyloid fibrils—the formation of which is a biomarker of Parkinson’s disease—were investigated using the fluorescent probe thioflavin T (ThT). The experimental conditions of protein fibrillogenesis were chosen so that a sufficient number of continuous measurements could be...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Sulatskaya, Anna I., Rodina, Natalia P., Sulatsky, Maksim I., Povarova, Olga I., Antifeeva, Iuliia A., Kuznetsova, Irina M., Turoverov, Konstantin K.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163839/
https://ncbi.nlm.nih.gov/pubmed/30142878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092486
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