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USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin

Synapse formation and growth are tightly controlled processes. How synaptic growth is terminated after reaching proper size remains unclear. Here, we show that Leon, the Drosophila USP5 deubiquitinase, controls postsynaptic growth. In leon mutants, postsynaptic specializations of neuromuscular junct...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Wang, Chien-Hsiang, Huang, Yi-Chun, Chen, Pei-Yi, Cheng, Ying-Ju, Kao, Hsiu-Hua, Pi, Haiwei, Chien, Cheng-Ting
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438252/
https://ncbi.nlm.nih.gov/pubmed/28489002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26886
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