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USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin

Synapse formation and growth are tightly controlled processes. How synaptic growth is terminated after reaching proper size remains unclear. Here, we show that Leon, the Drosophila USP5 deubiquitinase, controls postsynaptic growth. In leon mutants, postsynaptic specializations of neuromuscular junct...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Wang, Chien-Hsiang, Huang, Yi-Chun, Chen, Pei-Yi, Cheng, Ying-Ju, Kao, Hsiu-Hua, Pi, Haiwei, Chien, Cheng-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438252/
https://ncbi.nlm.nih.gov/pubmed/28489002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26886
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