L-selectin mechanochemistry restricts neutrophil priming in vivo

Circulating neutrophils must avoid premature activation to prevent tissue injury. The leukocyte adhesion receptor L-selectin forms bonds with P-selectin glycoprotein ligand-1 (PSGL-1) on other leukocytes and with peripheral node addressin (PNAd) on high endothelial venules. Mechanical forces can str...

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Publicat a:Nat Commun
Autors principals: Liu, Zhenghui, Yago, Tadayuki, Zhang, Nan, Panicker, Sumith R., Wang, Ying, Yao, Longbiao, Mehta-D'souza, Padmaja, Xia, Lijun, Zhu, Cheng, McEver, Rodger P.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437312/
https://ncbi.nlm.nih.gov/pubmed/28497779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15196
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