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Differential regulation of human and murine P-selectin expression and function in vivo

Leukocytes roll on P-selectin after its mobilization from secretory granules to the surfaces of platelets and endothelial cells. Tumor necrosis factor (TNF), IL-1β, and lipopolysaccharide increase synthesis of P-selectin in murine but not in human endothelial cells. To explore the physiological sign...

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Autors principals: Liu, Zhenghui, Miner, Jonathan J., Yago, Tadayuki, Yao, Longbiao, Lupu, Florea, Xia, Lijun, McEver, Rodger P.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005233/
https://ncbi.nlm.nih.gov/pubmed/21149548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101545
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