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Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain
RNA polymerase II contains a repetitive, intrinsically disordered, C-terminal domain (CTD) composed of heptads of the consensus sequence YSPTSPS. The CTD is heavily phosphorylated and serves as a scaffold, interacting with factors involved in transcription initiation, elongation and termination, RNA...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5437306/ https://ncbi.nlm.nih.gov/pubmed/28497792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15231 |
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