Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4

The T helper 9 (Th9) cell transcriptional network is formed by an equilibrium of signals induced by cytokines and antigen presentation. Here we show that, within this network, two interferon regulatory factors (IRF), IRF1 and IRF4, display opposing effects on Th9 differentiation. IRF4 dose-dependent...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Campos Carrascosa, Lucia, Klein, Matthias, Kitagawa, Yohko, Lückel, Christina, Marini, Federico, König, Anika, Guralnik, Anna, Raifer, Hartmann, Hagner-Benes, Stefanie, Rädler, Diana, Böck, Andreas, Kang, Cholho, Lohoff, Michael, Garn, Holger, Schaub, Bianca, Berberich-Siebelt, Friederike, Sakaguchi, Shimon, Bopp, Tobias, Huber, Magdalena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437292/
https://ncbi.nlm.nih.gov/pubmed/28497800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15366
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items