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Human cytomegalovirus induces and exploits Roquin to counteract the IRF1-mediated antiviral state

RNA represents a pivotal component of host–pathogen interactions. Human cytomegalovirus (HCMV) infection causes extensive alteration in host RNA metabolism, but the functional relationship between the virus and cellular RNA processing remains largely unknown. Through loss-of-function screening, we s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Song, Jaewon, Lee, Sanghyun, Cho, Dong-Yeon, Lee, Sungwon, Kim, Hyewon, Yu, Namhee, Lee, Sanghyuk, Ahn, Kwangseog
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6744924/
https://ncbi.nlm.nih.gov/pubmed/31451648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909314116
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