MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line

NRAS mutation in melanoma has been associated with aggressive tumor biology and poor prognosis. Although targeted therapy has been tested for NRAS mutated melanoma, response rates still appear much weaker, than in BRAF mutated melanoma. While plenty of cell lines exist, however, only few melanogenic...

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Pubblicato in:Sci Rep
Autori principali: Rinner, Beate, Gandolfi, Greta, Meditz, Katharina, Frisch, Marie-Therese, Wagner, Karin, Ciarrocchi, Alessia, Torricelli, Federica, Koivuniemi, Raili, Niklander, Johanna, Liegl-Atzwanger, Bernadette, Lohberger, Birgit, Heitzer, Ellen, Ghaffari-Tabrizi-Wizsy, Nassim, Zweytick, Dagmar, Zalaudek, Iris
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437015/
https://ncbi.nlm.nih.gov/pubmed/28522871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02197-y
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