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In vitro and in vivo cytotoxic activity of human lactoferricin derived antitumor peptide R-DIM-P-LF11-334 on human malignant melanoma

Di-peptides derived from the human host defense peptide lactoferricin were previously described to specifically interact with the negatively charged lipid phosphatidylserine exposed by cancer cells. In this study one further derivative, namely R-DIM-P-LF11-334 is shown to exhibit even increased canc...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Riedl, Sabrina, Rinner, Beate, Schaider, Helmut, Liegl-Atzwanger, Bernadette, Meditz, Katharina, Preishuber-Pflügl, Julia, Grissenberger, Sarah, Lohner, Karl, Zweytick, Dagmar
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641092/
https://ncbi.nlm.nih.gov/pubmed/29069749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17823
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