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Killing of melanoma cells and their metastases by human lactoferricin derivatives requires interaction with the cancer marker phosphatidylserine

Despite favorable advancements in therapy cancer is still not curative in many cases, which is often due to inadequate specificity for tumor cells. In this study derivatives of a short cationic peptide derived from the human host defense peptide lactoferricin were optimized in their selective toxici...

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Detalhes bibliográficos
Main Authors: Riedl, Sabrina, Rinner, Beate, Schaider, Helmut, Lohner, Karl, Zweytick, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155172/
https://ncbi.nlm.nih.gov/pubmed/24838743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-014-9749-0
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