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Killing of melanoma cells and their metastases by human lactoferricin derivatives requires interaction with the cancer marker phosphatidylserine

Despite favorable advancements in therapy cancer is still not curative in many cases, which is often due to inadequate specificity for tumor cells. In this study derivatives of a short cationic peptide derived from the human host defense peptide lactoferricin were optimized in their selective toxici...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Riedl, Sabrina, Rinner, Beate, Schaider, Helmut, Lohner, Karl, Zweytick, Dagmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155172/
https://ncbi.nlm.nih.gov/pubmed/24838743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10534-014-9749-0
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