MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line

NRAS mutation in melanoma has been associated with aggressive tumor biology and poor prognosis. Although targeted therapy has been tested for NRAS mutated melanoma, response rates still appear much weaker, than in BRAF mutated melanoma. While plenty of cell lines exist, however, only few melanogenic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rinner, Beate, Gandolfi, Greta, Meditz, Katharina, Frisch, Marie-Therese, Wagner, Karin, Ciarrocchi, Alessia, Torricelli, Federica, Koivuniemi, Raili, Niklander, Johanna, Liegl-Atzwanger, Bernadette, Lohberger, Birgit, Heitzer, Ellen, Ghaffari-Tabrizi-Wizsy, Nassim, Zweytick, Dagmar, Zalaudek, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437015/
https://ncbi.nlm.nih.gov/pubmed/28522871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02197-y
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