IRF5 distinguishes severe asthma in humans and drives Th1 phenotype and airway hyperreactivity in mice

Severe asthma (SA) is a significant problem both clinically and economically, given its poor response to corticosteroids (CS). We recently reported a complex type 1–dominated (IFN-γ–dominated) immune response in more than 50% of severe asthmatics despite high-dose CS treatment. Also, IFN-γ was found...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Oriss, Timothy B., Raundhal, Mahesh, Morse, Christina, Huff, Rachael E., Das, Sudipta, Hannum, Rachel, Gauthier, Marc C., Scholl, Kathryn L., Chakraborty, Krishnendu, Nouraie, Seyed M., Wenzel, Sally E., Ray, Prabir, Ray, Anuradha
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2017
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436536/
https://ncbi.nlm.nih.gov/pubmed/28515358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91019
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料