MMP-9 Inhibits IL-23p19 Expression in Dendritic Cells By Targeting Membrane Stem Cell Factor Affecting Lung IL-17 Response()

We previously reported that c-kit ligation by membrane-bound stem cell factor (mSCF) boosts IL-6 production in DCs and a Th17 immune response. However, Th17 establishment also requires heterodimeric IL-23 but the mechanisms that regulate IL-23 gene expression in DCs are not fully understood. Here we...

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Detalhes bibliográficos
Main Authors: Oriss, Timothy B., Krishnamoorthy, Nandini, Raundhal, Mahesh, Morse, Christina, Chakraborty, Krishnendu, Khare, Anupriya, Huff, Rachael, Ray, Prabir, Ray, Anuradha
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063408/
https://ncbi.nlm.nih.gov/pubmed/24829419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303183
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