Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation

Aging is the most important risk factor for neurodegenerative diseases associated with pathological protein aggregation such as Alzheimer’s disease. Although aging is an important player, it remains unknown which molecular changes are relevant for disease initiation. Recently, it has become apparent...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Groh, Nicole, Bühler, Anika, Huang, Chaolie, Li, Ka Wan, van Nierop, Pim, Smit, August B., Fändrich, Marcus, Baumann, Frank, David, Della C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434662/
https://ncbi.nlm.nih.gov/pubmed/28567012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00138
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