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The aggregation kinetics of Alzheimer’s β-amyloid peptide is controlled by stochastic nucleation
We report here a recombinant expression system that allows production of large quantities of Alzheimer’s Aβ(1–40) peptide. The material is competent to dissolve in water solutions with “random-coil properties,” although its conformation and factual oligomerization state are determined by the physico...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2253354/ https://ncbi.nlm.nih.gov/pubmed/15937275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.041266605 |
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