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NMR Assignments of Sparsely Labeled Proteins Using a Genetic Algorithm

Sparse isotopic labeling of proteins for NMR studies using single types of amino acid ((15)N or (13)C enriched) has several advantages. Resolution is enhanced by reducing numbers of resonances for large proteins, and isotopic labeling becomes economically feasible for glycoproteins that must be expr...

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Bibliographic Details
Published in:J Biomol NMR
Main Authors: Gao, Qi, Chalmers, Gordon R., Moremen, Kelley W., Prestegard, James H.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434516/
https://ncbi.nlm.nih.gov/pubmed/28289927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-017-0101-1
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