Investigating the Genetic Architecture of the PR Interval using Clinical Phenotypes

BACKGROUND: One potential use for the PR interval is as a biomarker of disease risk. We hypothesized that quantifying the shared genetic architectures of the PR interval and a set of clinical phenotypes would identify genetic mechanisms contributing to PR variability and identify diseases associated...

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Bibliographic Details
Published in:Circ Cardiovasc Genet
Main Authors: Mosley, Jonathan D., Shoemaker, M. Benjamin, Wells, Quinn S., Darbar, Dawood, Shaffer, Christian M., Edwards, Todd L., Bastarache, Lisa, McCarty, Catherine A., Thompson, Will, Chute, Christopher G., Jarvik, Gail P., Crosslin, David R., Larson, Eric B., Kullo, Iftikhar J., Pacheco, Jennifer A., Peissig, Peggy L., Brilliant, Murray H., Linneman, James G., Witte, John S., Denny, Josh C., Roden, Dan M.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434456/
https://ncbi.nlm.nih.gov/pubmed/28416512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.116.001482
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