USP22 Induces Cisplatin Resistance in Lung Adenocarcinoma by Regulating γH2AX-Mediated DNA Damage Repair and Ku70/Bax-Mediated Apoptosis

Resistance to platinum-based chemotherapy is one of the most important reasons for treatment failure in advanced non-small cell lung cancer, but the underlying mechanism is extremely complex and unclear. The present study aimed to investigate the correlation of ubiquitin-specific peptidase 22 (USP22...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Wang, Aman, Ning, Zhen, Lu, Chang, Gao, Wei, Liang, Jinxiao, Yan, Qiu, Tan, Guang, Liu, Jiwei
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434448/
https://ncbi.nlm.nih.gov/pubmed/28567015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00274
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