Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy

HIV and SIV infection dynamics are commonly investigated by measuring plasma viral loads. However, this total viral load value represents the sum of many individual infection events, which are difficult to independently track using conventional sequencing approaches. To overcome this challenge, we g...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS Pathog
Κύριοι συγγραφείς: Fennessey, Christine M., Pinkevych, Mykola, Immonen, Taina T., Reynaldi, Arnold, Venturi, Vanessa, Nadella, Priyanka, Reid, Carolyn, Newman, Laura, Lipkey, Leslie, Oswald, Kelli, Bosche, William J., Trivett, Matthew T., Ohlen, Claes, Ott, David E., Estes, Jacob D., Del Prete, Gregory Q., Lifson, Jeffrey D., Davenport, Miles P., Keele, Brandon F.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2017
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433785/
https://ncbi.nlm.nih.gov/pubmed/28472156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006359
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