Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy

HIV and SIV infection dynamics are commonly investigated by measuring plasma viral loads. However, this total viral load value represents the sum of many individual infection events, which are difficult to independently track using conventional sequencing approaches. To overcome this challenge, we g...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS Pathog
Hlavní autoři: Fennessey, Christine M., Pinkevych, Mykola, Immonen, Taina T., Reynaldi, Arnold, Venturi, Vanessa, Nadella, Priyanka, Reid, Carolyn, Newman, Laura, Lipkey, Leslie, Oswald, Kelli, Bosche, William J., Trivett, Matthew T., Ohlen, Claes, Ott, David E., Estes, Jacob D., Del Prete, Gregory Q., Lifson, Jeffrey D., Davenport, Miles P., Keele, Brandon F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433785/
https://ncbi.nlm.nih.gov/pubmed/28472156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006359
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky