Defining early SIV replication and dissemination dynamics following vaginal transmission

Understanding HIV transmission is critical to guide the development of prophylactic interventions to prevent infection. We used a nonhuman primate (NHP) model with a synthetic swarm of sequence-tagged variants of SIVmac239 (“SIVmac239X”) and scheduled necropsy during primary infection (days 3 to 14...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Deleage, Claire, Immonen, Taina T., Fennessey, Christine M., Reynaldi, Arnold, Reid, Carolyn, Newman, Laura, Lipkey, Leslie, Schlub, Timothy E., Camus, Celine, O’Brien, Sean, Smedley, Jeremy, Conway, Jessica M., Del Prete, Gregory Q., Davenport, Miles P., Lifson, Jeffrey D., Estes, Jacob D., Keele, Brandon F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541462/
https://ncbi.nlm.nih.gov/pubmed/31149634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav7116
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