Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy

HIV and SIV infection dynamics are commonly investigated by measuring plasma viral loads. However, this total viral load value represents the sum of many individual infection events, which are difficult to independently track using conventional sequencing approaches. To overcome this challenge, we g...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Fennessey, Christine M., Pinkevych, Mykola, Immonen, Taina T., Reynaldi, Arnold, Venturi, Vanessa, Nadella, Priyanka, Reid, Carolyn, Newman, Laura, Lipkey, Leslie, Oswald, Kelli, Bosche, William J., Trivett, Matthew T., Ohlen, Claes, Ott, David E., Estes, Jacob D., Del Prete, Gregory Q., Lifson, Jeffrey D., Davenport, Miles P., Keele, Brandon F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433785/
https://ncbi.nlm.nih.gov/pubmed/28472156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006359
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