Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus

The selective pressures acting on viruses that replicate under enhanced mutation rates are largely unknown. Here, we describe resistance of foot-and-mouth disease virus to the mutagen 5-fluorouracil (FU) through a single polymerase substitution that prevents an excess of A to G and U to C transition...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Biol Evol
Egile Nagusiak: de la Higuera, Ignacio, Ferrer-Orta, Cristina, de Ávila, Ana I., Perales, Celia, Sierra, Macarena, Singh, Kamalendra, Sarafianos, Stefan G., Dehouck, Yves, Bastolla, Ugo, Verdaguer, Nuria, Domingo, Esteban
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433387/
https://ncbi.nlm.nih.gov/pubmed/28460010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evx075
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak