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Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome
Dravet syndrome, an epileptic encephalopathy affecting children, largely results from heterozygous loss-of-function mutations in the brain voltage-gated sodium channel gene SCN1A. Heterozygous Scn1a knockout (Scn1a (+/−)) mice recapitulate the severe epilepsy phenotype of Dravet syndrome and are an...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431801/ https://ncbi.nlm.nih.gov/pubmed/28490751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01851-9 |
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