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Reconstruction of the Mouse Inflammasome System in HEK293T Cells

The NLRP3 (NLR family, Pyrin domain containing 3) inflammasome is a multiprotein complex comprised of NLRP3, pro-caspase-1, the adaptor protein apoptosis-associated speck-like protein containing a CARD (ASC), and the protein kinase NIMA related kinase 7 (NEK7) (Shi et al., 2016; He et al., 2016; Sch...

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Bibliografiske detaljer
Udgivet i:Bio Protoc
Main Authors: Shi, Hexin, Murray, Anne, Beutler, Bruce
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431583/
https://ncbi.nlm.nih.gov/pubmed/28516117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.1986
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