Evolution from adherent to suspension: systems biology of HEK293 cell line development

The need for new safe and efficacious therapies has led to an increased focus on biologics produced in mammalian cells. The human cell line HEK293 has bio-synthetic potential for human-like production attributes and is currently used for manufacturing of several therapeutic proteins and viral vector...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Malm, Magdalena, Saghaleyni, Rasool, Lundqvist, Magnus, Giudici, Marco, Chotteau, Veronique, Field, Ray, Varley, Paul G., Hatton, Diane, Grassi, Luigi, Svensson, Thomas, Nielsen, Jens, Rockberg, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7642379/
https://ncbi.nlm.nih.gov/pubmed/33149219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76137-8
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