HEK293T cell lines defective for O-linked glycosylation

Here we describe derivatives of the HEK293T cell line that are defective in their ability to generate mucin-type O-linked glycosylation. Using CRISPR/Cas9 and a single-cell GFP-sorting procedure, the UDP-galactose-4-epimerase (GALE), galactokinase 1 (GALK1), and galactokinase 2 (GALK2) genes were kn...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Termini, James M., Silver, Zachary A., Connor, Bryony, Antonopoulos, Aristotelis, Haslam, Stuart M., Dell, Anne, Desrosiers, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487050/
https://ncbi.nlm.nih.gov/pubmed/28654657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179949
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados