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Engineered HSV vector achieves safe long-term transgene expression in the central nervous system
Previously we reported a new series of highly defective herpes simplex virus type 1 (HSV-1) vectors that were functionally devoid of all viral immediately early (IE) genes, resulting in virtual absence of viral gene expression. Nevertheless, a reporter gene cassette inserted into the vector flanked...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431452/ https://ncbi.nlm.nih.gov/pubmed/28473703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01635-1 |
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