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Detection of SPG20 gene promoter-methylated DNA, as a novel epigenetic biomarker, in plasma for colorectal cancer diagnosis using the MethyLight method

Aberrant promoter methylation of genes is a common epigenetic alteration in colorectal cancer (CRC). In the present study, spastic paraplegia 20 (SPG20) promoter-methylated DNA, as a potential diagnostic biomarker, was investigated in plasma and tumor tissue samples from patients with CRC. To the be...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Rezvani, Nayebali, Alibakhshi, Reza, Vaisi-Raygani, Assad, Bashiri, Homayoon, Saidijam, Massoud
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431389/
https://ncbi.nlm.nih.gov/pubmed/28521434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.5815
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