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Protective effects of ascorbic acid against the genetic and epigenetic alterations induced by 3,5-dimethylaminophenol in AA8 cells

Exposure to monocyclic aromatic alkylanilines (MAAs), namely 2,6-dimethylaniline (2,6-DMA), 3,5-dimethylaniline (3,5-DMA) and 3-ethylaniline (3-EA), was significantly and independently associated with bladder cancer incidence. 3,5-DMAP (3,5-dimethylaminophenol), a metabolite of 3,5-DMA, was shown to...

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Detalhes bibliográficos
Publicado no:J Appl Toxicol
Main Authors: Chao, Ming-Wei, Erkekoglu, Pınar, Tseng, Chia-Yi, Ye, Wenjie, Trudel, Laura J., Skipper, Paul L., Tannenbaum, Steven R., Wogan, Gerald N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431077/
https://ncbi.nlm.nih.gov/pubmed/25178734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3046
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