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Transimination of Quinone Imines: A Mechanism for Embedding Exogenous Redox Activity into the Nucleosome
[Image: see text] Aminophenols can redox cycle through the corresponding quinone imines to generate ROS. The electrophilic quinone imine intermediate can react with protein thiols as a mechanism of immobilization in vivo. Here, we describe the previously unkown transimination of a quinone imine by l...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525013/ https://ncbi.nlm.nih.gov/pubmed/23194336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3004517 |
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