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Hydroxyphenylation of Histone Lysines: Post-translational Modification by Quinone Imines

Monocyclic aromatic amines are widespread environmental contaminants with multiple sources such as combustion products, pharmaceuticals, and pesticides. Their phenolic metabolites are converted intracellularly to electrophilic quinone imines upon autoxidation and can embed in the cellular matrix thr...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Ravindra, Kodihalli C., Trudel, Laura J., Wishnok, John S., Wogan, Gerald N., Tannenbaum, Steven R., Skipper, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495105/
https://ncbi.nlm.nih.gov/pubmed/26866676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00923
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