ロード中...
The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington’s disease patients
We have previously shown that exon 1 of the huntingtin gene does not always splice to exon 2 resulting in the production of a small polyadenylated mRNA (HTTexon1) that encodes the highly pathogenic exon 1 HTT protein. The level of this read-through product is proportional to CAG repeat length and is...
保存先:
| 出版年: | Sci Rep |
|---|---|
| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431000/ https://ncbi.nlm.nih.gov/pubmed/28465506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01510-z |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|