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Role of the Ion Channel Extracellular Collar in AMPA Receptor Gating

AMPA subtype ionotropic glutamate receptors mediate fast excitatory neurotransmission and are implicated in numerous neurological diseases. Ionic currents through AMPA receptor channels can be allosterically regulated via different sites on the receptor protein. We used site-directed mutagenesis and...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Yelshanskaya, Maria V., Mesbahi-Vasey, Samaneh, Kurnikova, Maria G., Sobolevsky, Alexander I.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430913/
https://ncbi.nlm.nih.gov/pubmed/28432359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01146-z
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