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Role of the Ion Channel Extracellular Collar in AMPA Receptor Gating

AMPA subtype ionotropic glutamate receptors mediate fast excitatory neurotransmission and are implicated in numerous neurological diseases. Ionic currents through AMPA receptor channels can be allosterically regulated via different sites on the receptor protein. We used site-directed mutagenesis and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Yelshanskaya, Maria V., Mesbahi-Vasey, Samaneh, Kurnikova, Maria G., Sobolevsky, Alexander I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430913/
https://ncbi.nlm.nih.gov/pubmed/28432359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01146-z
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