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Role of the Ion Channel Extracellular Collar in AMPA Receptor Gating

AMPA subtype ionotropic glutamate receptors mediate fast excitatory neurotransmission and are implicated in numerous neurological diseases. Ionic currents through AMPA receptor channels can be allosterically regulated via different sites on the receptor protein. We used site-directed mutagenesis and...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Yelshanskaya, Maria V., Mesbahi-Vasey, Samaneh, Kurnikova, Maria G., Sobolevsky, Alexander I.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430913/
https://ncbi.nlm.nih.gov/pubmed/28432359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01146-z
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